- 1. The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer ...
- (Ivermectin)
- ... and the exploration of the macrocyclic lactone chemical space. Given that Ivermectin is a safe anti-parasitic agent used by > 200 million people against river blindness, our results suggest its additional ...
- Created on 20 August 2014
- 2. Ivermectin for COVID-19: real-time meta analysis of 78 studies
- (Ivermectin)
- ... average treatment delay 2.9 days, dosage 200μg/kg days 1-3, this trial uses multiple treatments in the treatment arm (combined with AZ, nitazoxanide (82), HCQ (22), spironolactone (66), dutasteride (4)) - resu ...
- Created on 05 February 2022
- 3. Effectiveness of ivermectin-based multidrug therapy in severely hypoxic, ambulatory COVID-19 patients
- (Ivermectin)
- Aims: Ivermectin is a safe, inexpensive and effective early COVID-19 treatment validated in 20+ random, controlled trials. Having developed combination therapies for Helicobacter pylori, the authors ...
- Created on 10 January 2022
- 4. The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review
- (Ivermectin)
- ... consumption since the early 1980s. Ivermectin belongs to a group of avermectins, which is a group of 16 membered macrocyclic lactone compounds discovered at the Japanese Kitasato Institute in 1967 during ...
- Created on 21 December 2021
- 5. Ivermectin, a potential anticancer drug derived from an antiparasitic drug
- (Ivermectin)
- ... bMed] [CrossRef] [Google Scholar] 41. Melotti A., Mas C., Kuciak M., Lorente-Trigos A., Borges I., Ruiz i Altaba A. The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF p ...
- Created on 21 September 2021
- 6. Vaccines and allergic reactions: The past, the current COVID‐19 pandemic, and future perspectives
- (Uncategorised)
- ... contact dermatitis, it is considered irrelevant to vaccine‐induced anaphylaxis. 116 Formaldehyde and beta‐propiolactone (BPL) have been used to inactivate viruses during the production of vaccines. ...
- Created on 14 September 2021
- 7. Antivirals that target the host IMPα/β1-virus interface
- (Anti-Viral Research)
- ... IMPα/β1 directly include the FDA-approved macrocyclic lactone ivermectin, which has documented broad-spectrum activity against a whole range of viruses, including HIV-1, DENV1–4, ZIKV, West Nile virus ...
- Created on 31 January 2021
- 8. North Wales child abuse scandal
- (Paedophile Rings)
- ... led verification] Clwyd Council owned: Bryn Estyn; Cartrefle; Little Acton Assessment Centre; Bersham Hall; Chevet Hey; Park House; Upper Downing; South Meadow; Ysgol Talfryn Privately owned: ...
- Created on 17 October 2019
- 9. Ivermectin reverses the drug resistance in cancer cells through EGFR/ERK/Akt/NF-κB pathway
- (Ivermectin)
- ... olar 19. Melotti A, Mas C, Kuciak M, Lorente-Trigos A, Borges I, Ruiz i Altaba A. The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human ca ...
- Created on 18 June 2019
- 10. Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations
- (Ivermectin)
- ... it as a complex mixture of 16-membered macrocyclic lactones produced by fermentation of the actinomycete Streptomyces avermitilis—later re-classified as S. avermectinius (Figure 2). The avermectin famil ...
- Created on 15 February 2017
- 11. Ivermectin induces cytostatic autophagy by blocking the PAK1/Akt axis in breast cancer
- (Ivermectin)
- ... Lorente-Trigos A, Borges I, Ruiz i Altaba A . The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer. EMBO Mol Med 2014;6:1263–78. ...
- Created on 28 August 2016
- 12. Severe Acute Respiratory Syndrome-Associated Coronavirus vaccines formulated with Delta Inulin adjuvants provide enhanced protection while ameliorating Lung Eosinophilic Immunopathology
- (Coronavirus Vaccines Leads to Pulmonary and Lung Immunopathology)
- ... y, NIAID, NIH: formaldehyde- and UV-inactivated, purified SARS-CoV vaccine NR-3882; SARS-CoV spike protein NR-722; β-propiolactone-inactivated, alum-adsorbed SARS-CoV NR-9599; and formaldehyde-and UV inactiva ...
- Created on 15 March 2015
- 13. "How Child Protection Services Buys and Sells Our Children"
- (Uncategorised)
- ... the area of minor children making medical decisions. Vernonia School District 47J v. Acton, 132 L.Ed.2d 564, 115 S.Ct. 2386 (1995) In Vernonia the Court strengthened parental rights by approaching the ...
- Created on 06 August 2012
- 14. Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus
- (Covid Vaccine Induced Myocarditis)
- ... . The other whole virus vaccine was prepared in Vero cells, concentrated, purified, inactivated with beta propiolactone and packaged with alum adjuvant (BPV) [13]. A recombinant DNA spike (S) protein vacci ...
- Created on 20 April 2012
- 15. Ivermectin, ‘Wonder drug’ from Japan: the human use perspective
- (Ivermectin)
- ... Unlike DEC, it is believed that the large molecular size of ivemectin, a macrocylic lactone, prevents it from crossing the blood/aqueous humour barrier, stopping it entering the anterior chamber and exerting ...
- Created on 10 February 2011
- 16. Another family court attrocity
- (Family court judgements where the perp is given custody after the child or children disclose sexual abuse)
- ... e Acton made a ruling that the father of Casey and his younger brother should be awarded sole custody and that their mother, Rondi Anderson, should have no contact with her boys whatsoever. Recently Cas ...
- Created on 21 February 2010