- 1. HIV-based lentiviral vectors: Origin and sequence differences
- (HIV based Lentiviral Vectors)
- ... ΔU3 in the SIN LTR with the reference viruses in culture or in disease progression in patients. Higher steady-state viral loads or greater viral replication could correspond to a more active 3′ LTR, and ...
- Created on 30 March 2022
- 2. Ivermectin for COVID-19: real-time meta analysis of 78 studies
- (Ivermectin)
- ... Highlights Ivermectin reduces risk for COVID-19 with very high confidence for mortality, ICU admission, hospitalization, progression, recovery, cases, viral clearance, and in pooled analysis, ...
- Created on 05 February 2022
- 3. Myocarditis cases reported after mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021
- (Covid Vaccine Induced Myocarditis)
- Key Points Question: What is the risk of myocarditis after mRNA-based COVID-19 vaccination in the US? Findings: In this descriptive study of 1626 cases of myocarditis in a national passive reporting ...
- Created on 25 January 2022
- 4. Effectiveness of ivermectin-based multidrug therapy in severely hypoxic, ambulatory COVID-19 patients
- (Ivermectin)
- Aims: Ivermectin is a safe, inexpensive and effective early COVID-19 treatment validated in 20+ random, controlled trials. Having developed combination therapies for Helicobacter pylori, the authors ...
- Created on 10 January 2022
- 5. The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review
- (Ivermectin)
- ... SARS-CoV-2 viral load, disease severity, and progression [50]. COVID-19 not only causes flu-like symptoms such as fever, dry cough but could also lead to widespread thrombosis with microangiopathy in pulmonary ...
- Created on 21 December 2021
- 6. A Report on Myocarditis Adverse Events in the U.S. Vaccine Adverse Events Reporting System (VAERS) in Association with COVID-19 Injectable Biological Products
- (Covid Vaccine Induced Myocarditis)
- Following the global rollout and administration of the Pfizer Inc./BioNTech BNT162b2 and Moderna mRNA-1273 vaccines on December 17, 2020, in the United States, and of the Janssen Ad26.COV2.S product ...
- Created on 01 November 2021
- 7. Retracted coronavirus (COVID-19) papers
- (Covid Vaccine Research)
- ... 2020 as a duplicate publication by journal error. “Liver impairment associated with disease progression in COVID‐19 patients,” published April 15, 2020 in Liver International and retracted in August/September ...
- Created on 26 October 2021
- 8. Ivermectin for prevention and treatment of COVID-19 infection: A systematic review, meta-analysis, and trial sequential analysis to inform clinical guidance
- (Ivermectin)
- ... VID (outpatients) 24 0.4 mg/kg × 1 dose Placebo Published in PR journal PCR +ve at day 7, proportion symptomatic at day 4,7,14,21, progression, death, adverse events Chachar 2020112 Paki ...
- Created on 22 October 2021
- 9. Melatonin interferes with COVID-19 at several distinct ROS-related steps
- (Covid Health Resources)
- ... agent for COVID-19 recently, having been given with a US Food and Drug Administration emergency authorized cocktail, REGEN-COV2, for management of COVID-19 progression. This review distinctly highlight ...
- Created on 22 October 2021
- 10. Ivermectin, a potential anticancer drug derived from an antiparasitic drug
- (Ivermectin)
- ... g D., Lin D. Ivermectin inhibits canine mammary tumor growth by regulating cell cycle progression and WNT signaling. BMC Vet Res. 2019;15(1):276. doi: 10.1186/s12917-019-2026-2. [PMC free article] [PubMed] [CrossRef] [ ...
- Created on 21 September 2021
- 11. Analysis of the effects of COVID-19 mask mandates on hospital resource consumption and mortality at the county level
- (Covid and Face Masks)
- ... several countermeasures to slow its progression, including but not limited to border closures, school and nonessential business closings, quarantine restrictions, stay-at-home orders, social distancing ...
- Created on 03 September 2021
- 12. Clinical Trials for Use of Melatonin to Fight against COVID-19 Are Urgently Needed
- (Covid Health Resources)
- ... pathology; these are caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This leads to a cytokine storm and subsequent progression triggering acute lung injury (ALI)/acute respiratory ...
- Created on 24 August 2021
- 13. Melatonin as a potential adjuvant treatment for COVID-19 beyond sleep disorders
- (Covid Health Resources)
- ... preclinical data suggest that melatonin may inhibit COVID-19 progression. It may lower the risk of the entrance of the SARS-CoV-2 virus into cells, reduce uncontrolled hyper-inflammation and the activation ...
- Created on 11 August 2021
- 14. Prescription, over-the-counter (OTC), herbal, and other treatments and preventive uses for COVID-19
- (Covid Research)
- ... a synergistic effect against SARS-CoV-2.114 , 115 The possible antiinflammatory properties of azithromycin, which could improve the disease progression, was also reported.114 , 115 However, its administration ...
- Created on 28 June 2021
- 15. Review of the emerging evidence demonstrating the efficacy of Ivermectin in the prophylaxis and treatment of COVID-19
- (Ivermectin)
- ... progression to prevent hospitalization. More recently, trial results of ivermectin, a widely used antiparasitic medicine with known antiviral and anti-inflammatory properties, have been showing benefits ...
- Created on 22 April 2021
- 16. Review of the emerging evidence demonstrating the efficacy of Ivermectin in the prophylaxis and treatment of Covid-19
- (Ivermectin)
- ... is the fact that no agent has yet proven effective in outpatients to prevent disease progression to prevent hospitalization. More recently, trial results of ivermectin, a widely used antiparasitic medicine ...
- Created on 22 April 2021
- 17. A Proteome-Wide Immunoinformatics Tool to Accelerate T-Cell Epitope Discovery and Vaccine Design in the Context of Emerging Infectious Diseases: An Ethnicity-Oriented Approach
- (HIV based Lentiviral Vectors)
- Emerging infectious diseases (EIDs) caused by viruses are increasing in frequency, causing a high disease burden and mortality world-wide. The COVID-19 pandemic caused by the novel SARS-like coronavirus ...
- Created on 26 February 2021
- 18. Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
- (Covid Research)
- ... disease progression, a conclusion supported by analyses of the combined outcome of death or ventilation initiation. Although assignment to any of the active trial treatments in this open-label trial ...
- Created on 11 February 2021
- 19. Ivermectin presents effective and selective antileishmanial activity
- (Ivermectin)
- ... and Evans 2014). On the contrary, a Th2-type immune response based on the production of cytokines such as IL-4, IL-5 and IL-10, contributes to disease progression by deactivation of parasitized macrophage ...
- Created on 01 February 2021
- 20. Antivirals that target the host IMPα/β1-virus interface
- (Anti-Viral Research)
- ... to limit VEEV infection in cell culture (EC50 of 10.8 μM) [16]; subsequent work indicated that G281–1564 prevents delays in cell cycle progression, which in part may depend on CP nuclear localisation/ IMPα/β ...
- Created on 31 January 2021
- 21. Facemasks in the COVID-19 era: A health hypothesis
- (Covid and Face Masks)
- ... consequences. Prolonged hypoxic-hypercapnic state compromises normal physiological and psychological balance, deteriorating health and promotes the developing and progression of existing chronic diseases [23], [38], [39], [43], [47], [48], [57], [11], [12], [13]. ...
- Created on 22 November 2020
- 22. The molecule for our times
- (Covid Health Resources)
- ... cold virus infection. The need for early treatment to prevent progression to ventilators is needed. Patients with suspected COVID-19 coronavirus infection as evidenced by symptoms of loss of smell, shortness ...
- Created on 27 April 2020
- 23. Paula Carew
- (Australian public guardian corruption)
- ... the court room on the progression of Mr Carew’s dementia and that Mr Carew’s daughter who had been looking after her father for 20 years, did not have the qualifications to look after her father. The Judge ...
- Created on 21 July 2019
- 24. Children suffering deprevation while in child placement
- (Uncategorised)
- ... igating the case as a death. (Left age 11, middle photo is an age progression, right 2 years) Date: 1999-01-01 Placement type: Adoption Type of abuse: Non-lethal physical abuse, Non-lethal deprivation, ...
- Created on 19 July 2019
- 25. Lentiviral Vector-Based Dendritic Cell Vaccine Suppresses HIV Replication in Humanized Mice
- (HIV based Lentiviral Vectors)
- ... with advanced cellular dysfunction and disease progression, 12 , 13 , 14 , 15 suggesting that checkpoint engagement is an important regulator of immune exhaustion in HIV-infection. In ...
- Created on 15 March 2019
- 26. GABA, γ-Aminobutyric Acid, protects against severe liver injury
- (Scientific Publications)
- Background: Acute liver failure (ALF) from severe acute liver injury is a critical condition associated with high mortality. The purpose of this study was to investigate the impact of preemptive ...
- Created on 17 December 2018
- 27. Ivermectin promotes peripheral nerve regeneration during wound healing
- (Ivermectin)
- ... untreated and served as additional controls. Both wounds were sealed using Tegaderm, and wound progression was followed over the course of 12 days. We determined that ivermectin partially aided in wound ...
- Created on 01 October 2018
- 28. How the elderly lose their rights
- (Guardianship)
- ... to myself, Well, when family members die they pass it down to their children. Isn’t that just the normal progression of things?” After a few months on the job, Clifton was asked to work as a guardian, ...
- Created on 09 October 2017
- 29. Inala siblings who never came home among the many missing people across nation
- (Tennant Creek - Mount Isa)
- ... olved. Assistant Commissioner Platz said police relied on the community and age progression images to help with unsolved cases. "For police, it is very important we get the information and our greates ...
- Created on 30 July 2017
- 30. A review on various Uues of N-Acetyl Cysteine
- (Covid Health Resources)
- ... vulnerable individuals when they are older (55,56). A wide range of both genetic and environmental factors have been proposed as contributing to the initiation and progression of PD, but aging is the singl ...
- Created on 19 June 2017
- 31. Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations
- (Ivermectin)
- ... have also been linked to rosacea, a chronic skin condition that manifests as recurrent inflammatory lesions. Long-term treatment is required to control symptoms and disease progression, with topical medicament ...
- Created on 15 February 2017
- 32. Ivermectin induces cytostatic autophagy by blocking the PAK1/Akt axis in breast cancer
- (Ivermectin)
- ... as a consequence of chemotherapy or radiotherapy; however, the role that autophagy plays in cancer progression is varied (34). Generally, autophagy is considered as a prosurvival mechanism in cancer cells ...
- Created on 28 August 2016
- 33. DPP (Cth) v McIntosh [2016] VCC 622 (19 May 2016)
- (Paedophile Protecting Judges)
- ... on outlined to me. Unfortunately, these phases reflect progression into further serious offending, and some of it significant escalation in the nature of the offending. What I regard as the first ph ...
- Created on 19 May 2016
- 34. Immunodominant SARS coronavirus epitopes in humans elicited both enhancing and neutralizing effects on infection in non-human primates
- (Covid Vaccine Research)
- ... Ryan Zurakowski, Catherine A. Fromen, Jason P. Gleghorn. Significant Unresolved Questions and Opportunities for Bioengineering in Understanding and Treating COVID-19 Disease Progression. Cellular and Molecu ...
- Created on 13 March 2016
- 35. Diagnosis of myocarditis: Current state and future perspectives
- (Covid Vaccine Induced Myocarditis)
- ... such as chest pain, dyspnea and palpitations. The pathophysiological process of disease progression leading to DCM involves an ongoing inflammation as a result of a viral-induced auto-immune response or ...
- Created on 15 July 2015
- 36. Anti-inflammatory, Antioxidant and Antimicrobial Effects of Artemisinin Extracts from Artemisia annua L.
- (Covid Health Resources)
- ... the progression of periodontal disease. It is one of the characteristic species frequently isolated from infected gingival pockets indicating it is a potential periodontal pathogen [17]. Prevotella intermedia i ...
- Created on 31 December 2014
- 37. The New King - But the first wrong was not his. Nor was the first wrong the government's. The first wrong was ours.
- (Uncategorised)
- ... our freedom has been a part of an insidious progression. In the beginning the attention of the flock was directed not to the marauding wolf but to our own deviant members within the flock. We rejoice ...
- Created on 29 August 2011
- 38. Over 50 percent of Mullighan Inquiry victims reject government offer
- (Paedophile Victims)
- ... for ex gratia payments and will seek private settlements from the State Government. John Rau speaks with Matthew Abraham about the Mullighan Inquiry progression. (Brett Williamson - ABC Adelaide) ...
- Created on 16 February 2011
- 39. The Therapeutic Potential of Melatonin: A Review of the Science
- (Covid Health Resources)
- ... nd methylphenyltetrahydropyridine- (MPTP) induced damage to the substantia nigra in experimental parkinsonism, and thus prevented disease progression in these animals.[97] Melatonin pretreatment reduced cereb ...
- Created on 14 April 2004
- 40. Inhibition of HIV-1 infection by lentiviral vectors expressing pol III-promoted anti-HIV RNAs
- (HIV based Lentiviral Vectors)
- ... of surface expression of this receptor confers strong resistance to HIV-1 infection [ 30 , 31 ]. Individuals heterozygous for the deletion (CCR5Δ32/CCR5) exhibit slower disease progression [ 32 ...
- Created on 01 August 2003